Chemopreventive Activity of Maharishi Arnrit Kalash [MAK-4 and MAK-5] and Related Agents in Rat Tracheal Epithelial and Human Tumor Cells
Proceedings of the American Association for Cancer Research, Vol. 32, p. 128, 1991 (Abstract).
J.T. Arnold,* B.P. Wilkinson,* E.A. Korytynski,* and V.E. Steele.**
* ManTech Environmental Technology, Inc., RTP, NC 27709
**National Cancer Institute, Bethesda, MD 20892
...results suggest that MAK-4 and MAK-5 inhibit processes of neoplastic transformation. Compounds tested in these assays that are similar to the ingredients in MAK-4 and MAK-5 also show chemopreventive activity. These include curcumin, ferulic acid, catechin, bioflavonoids, retinoic acid, ascorbyl palmitate, and glycyrrhetinic acid.
Antioxidant Adjuvant Therapy Using Natural Herbal Mixtures [MAK-4 and MAK-3] During Intensive Chemotherapy: Reduction in Toxicity. A Prospective Study of 62 Patients
Rao, R.S., Deo, M.G., and Sanghvi, L.D. (eds). Proceedings of the XVI International Cancer Congress. Bologna, Italy: Monduzzi Editore, 1994: pp. 3099-3102.
N.C. Misra,* H.M. Sharma,** A. Chaturvedi,* Ramakant,* S. Srivastav,* V. Devi,* P. Kakkar,t Vishwanathan.t S.M. Natu,* andJ. Bogra*
* K.G. Medical College, Lucknow, India **The Ohio State University, Columbus, OH & Indian Toxicology Research Centre, Lucknow, India
MAK-4 and MAK-5 supplementation was effective in reducing toxic chemotherapy side effects in patients undergoing intensive chemotherapy. Patients receiving the supplements experienced reduced hematologic toxicity, vomiting, and diarrhea, and improved sleep, weight, and well-being.