Research on Reduction of Chemical Toxicity

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Antioxidant Properties of Two Ayurvedic Herbal Preparations [MAK-4 and MAK-3]

Toluene is an organic solvent widely used in industry. Exposure to toluene can result in neuronal damage, as manifested by neurobehavioral and electrophysiological effects in humans and rats..... rats pretreated with MAK-5 showed a significant decrease in toluene-induced ROS in the cerebellar synaptosomal/mitochondrial preparations (p<0.03). Also, the alcoholic extract of MAK-5 significantly reduced toluene-induced ROS generation (p<0.03) in the kidney mitochondrial fraction.